TY  - JOUR
AU  - Parrilla-Doblas, Jara Teresa
AU  - Ariza, Rafael R
AU  - Roldan-Arjona, Teresa
PY  - 2017
DO  - 10.1080/15592294.2017.1294306
UR  - http://hdl.handle.net/10668/10948
T2  - Epigenetics
AB  - DNA methylation is a crucial epigenetic mark associated to gene silencing, and its targeted removal is a major goal of epigenetic editing. In animal cells, DNA demethylation involves iterative 5mC oxidation by TET enzymes followed by...
LA  - en
PB  - Taylor & Francis
KW  - 5-methylcytosine
KW  - Base excision repair
KW  - DNA demethylation
KW  - DNA glycosylase
KW  - DNA methylation
KW  - Epigenetic editing
KW  - Transcriptional silencing
KW  - 5-Methylcytosine
KW  - DNA glycosylases
KW  - DNA methylation
KW  - Gene silencing
KW  - HEK293 cells
KW  - Humans
KW  - Plants
KW  - Transcriptional activation
TI  - Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain.
TY  - research article
VL  - 12
ER  -