RT Journal Article
T1 Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study.
A1 Arroyo-Olivares, Raquel
A1 Alonso, Rodrigo
A1 Quintana-Navarro, Gracia
A1 Fuentes-Jimenez, Francisco
A1 Mata, Nelva
A1 Muñiz-Grijalvo, Ovidio
A1 Diaz-Diaz, Jose L
A1 Zambon, Daniel
A1 Arrieta, Francisco
A1 Garcia-Cruces, Jesus
A1 Garrido-Sanjuan, Juan A
A1 Banegas, Jose R
A1 Mata, Pedro
K1 Diet
K1 Familial hypercholesterolaemia
K1 Fatty acids
K1 Mediterranean diet
K1 Physical activity
AB Healthy lifestyle habits are the cornerstone in the management of familial hypercholesterolaemia (FH). Nevertheless, dietary studies on FH-affected populations are scarce. The present study analyses dietary habits, adherence to a Mediterranean diet pattern and physical activity in an adult population with FH and compares them with their non-affected relatives. Cross-sectional study. Data came from SAFEHEART, a nationwide study in Spain.ParticipantsIndividuals (n 3714) aged ≥18 years with a genetic diagnosis of FH (n2736) and their non-affected relatives (n 978). Food consumption was evaluated using a validated FFQ. Total energy intake was lower in FH patients v. non-affected relatives (P<0·005). Percentage of energy from fats was also lower in the FH population (35 % in men, 36 % in women) v. those non-affected (38 % in both sexes, P<0·005), due to the lower consumption of saturated fats (12·1 % in FH patients, 13·2 % in non-affected, P<0·005). Consumption of sugars was lower in FH patients v. non-affected relatives (P<0·05). Consumption of vegetables, fish and skimmed milk was higher in the FH population (P<0·005). Patients with FH showed greater adherence to a Mediterranean diet pattern v. non-affected relatives (P<0·005). Active smoking was lower and moderate physical activity was higher in people with FH, especially women (P<0·005). Adult patients with FH report healthier lifestyles than their non-affected family members. They eat a healthier diet, perform more physical activity and smoke less. However, this patient group's consumption of saturated fats and sugars still exceeds guidelines.
PB Cambridge University Press
YR 2018
FD 2018-12-05
LK http://hdl.handle.net/10668/13531
UL http://hdl.handle.net/10668/13531
LA en
NO Arroyo-Olivares R, Alonso R, Quintana-Navarro G, Fuentes-Jiménez F, Mata N, Muñiz-Grijalvo O, et al. Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study. Public Health Nutr. 2019 Jun;22(8):1433-1443
NO This work was supported by Fundación Hipercolesterolemia Familiar; the Instituto de Salud Carlos III (ISCIII; grant numbers G03/181 and FIS PI12/01289); and Centro Nacional de Investigación Cardiovascular (CNIC; grantnumber 08-2008).
DS RISalud
RD Apr 5, 2025