TY - JOUR AU - Teuwen, Laure-Anne AU - De Rooij, Laura P. M. H. AU - Cuypers, Anne AU - Rohlenova, Katerina AU - Dumas, Sébastien J. AU - García-Caballero, Melissa AU - Meta, Elda AU - Amersfoort, Jacob AU - Taverna, Federico AU - Becker, Lisa M. AU - Veiga, Nuphar AU - Cantelmo, Anna Rita AU - Geldhof, Vincent AU - Conchinha, Nadine V. AU - Kalucka, Joanna AU - Treps, Lucas AU - Conradi, Lena-Christin AU - Khan, Shawez AU - Karakach, Tobias K. AU - Soenen, Stefaan AU - Vinckier, Stefan AU - Schoonjans, Luc AU - Eelen, Guy AU - Van Laere, Steven AU - Dewerchin, Mieke AU - Dirix, Luc AU - Mazzone, Massimiliano AU - Luo, Yonglun AU - Vermeulen, Peter AU - Carmeliet, Peter PY - 2021 DO - 10.1016/j.celrep.2021.109253 UR - http://hdl.handle.net/10668/3614 T2 - Cell Reports AB - Tumor vessel co-option is poorly understood, yet it is a resistance mechanism against anti-angiogenic therapy (AAT). The heterogeneity of co-opted endothelial cells (ECs) and pericytes, co-opting cancer and myeloid cells in tumors growing via vessel... LA - en PB - Cell Press KW - Tumor vessel co-option KW - Tumor angiogenesis KW - Anti-angiogenic therapy KW - Metastasis KW - Resistance KW - Single-cell RNA sequencing KW - Endothelial cells KW - Pericytes KW - Macrophages KW - Cancer cells KW - Inductores de la angiogénesis KW - Metástasis de la neoplasia KW - Células endoteliales KW - Pericitos KW - Macrófagos KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Urologic Neoplasms::Kidney Neoplasms KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred BALB C KW - Medical Subject Headings::Anatomy::Cells::Myeloid Cells KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Anatomy::Cells::Pericytes KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Cytological Techniques::Single-Cell Analysis TI - Tumor vessel co-option probed by single-cell analysis TY - research article ER -