RT Journal Article
T1 Oral florid papillomatosis: Topical treatment with 5% imiquimod in orabase.
A1 Ruiz-Huertas, Pedro
A1 Borrego-Luque, Alicia
A1 Toledano-Valero, Pilar
A1 Manzotti, Carolina
A1 Rollón-Mayordomo, Ángel
K1 imiquimod
K1 immunotherapy
K1 oral florid papillomatosis
K1 oral mucosa
AB Florid oral papillomatosis is characterized by its tendency to local recurrence that requires multiple treatments, leading to important functional sequelae. We present 74-year-old woman with oral florid papillomatosis (OFP) who refused a new surgical treatment, and was treated with imiquimod 5% in orabase on alternate days for 16 weeks. Treatment was complemented with application of hyaluronic acid gel. There were no side effects to the treatment, nor signs of local recurrence, in the treated area at 2 years of follow-up. After reviewing the literature and according to our knowledge, this is the first published case of oral florid papillomatosis treated topically with imiquimod 5% successfully. Topical treatment with imiquimod 5% in orabase may be a valid alternative for patients with recurrent OFP located in the anterior area of the oral cavity who refuse surgical treatment, although we must closely monitor the patient for the possibility of recurrence or malignant degeneration.
YR 2022
FD 2022-04-13
LK http://hdl.handle.net/10668/21840
UL http://hdl.handle.net/10668/21840
LA en
DS RISalud
RD Apr 6, 2025