RT Journal Article
RT Journal Article
T1 Relationship between insulin-biochemical resistance levels and the degree of depression and anxiety in patients from Honduras
A1 Pablo Diaz-Carias, Juan
A1 Morilla Romero de la Osa, Ruben
A1 Cano-Rodriguez, Mercedes
K1 Depression
K1 Anxiety
K1 Insulin Resistance
K1 Obesity
K1 Gender-differences
K1 Obesity
K1 Symptoms
K1 Association
AB Background/purpose Many studies suggest that insulin resistance in obese patients bridges mental illness. Our objective was to identify the association between levels of depression and anxiety with insulin resistance, and its relationship with obesity and abdominal obesity Methods A cross-sectional analytical study was carried out in Honduras. Sociodemographic variables, anthropometric parameters, HOMA index, and level of severity of anxiety and depression were collected, and a descriptive, bivariate, and multivariate were performed. Results In a sample of 381 adult patients, the bivariate analysis showed a statistic association of insulin resistance with all remaining variables. However, multivariate analysis showed a significative association of anxiety with BMI, depression, waist circumference, and insulinemia, while depression was associated with HOMA, anxiety, insulinemia, glycemia, and waist circumference. Conclusions Our results provide important evidence of a direct and growing association between HOMA-IR and the severity of depression, and indirectly with anxiety. Secondarily, also with anthropometric factors (BMI and WC), traditionally associated with cardiovascular risk. This finding has important implications both for the early diagnosis of these mental pathologies, taking into account HOMA-IR values, and for preventive interventions focused on maintaining blood insulin levels.
PB Springer india
SN 0973-3930
YR 2022
FD 2022-07-28
LK http://hdl.handle.net/10668/21441
UL http://hdl.handle.net/10668/21441
LA en
DS RISalud
RD Apr 9, 2025