RT Journal Article
T1 What pulmonologists think about the asthma-COPD overlap syndrome.
A1 Miravitlles, Marc
A1 Alcázar, Bernardino
A1 Alvarez, Francisco Javier
A1 Bazús, Teresa
A1 Calle, Myriam
A1 Casanova, Ciro
A1 Cisneros, Carolina
A1 de-Torres, Juan P
A1 Entrenas, Luis M
A1 Esteban, Cristóbal
A1 García-Sidro, Patricia
A1 Cosio, Borja G
A1 Huerta, Arturo
A1 Iriberri, Milagros
A1 Izquierdo, José Luis
A1 López-Viña, Antolín
A1 López-Campos, José Luis
A1 Martínez-Moragón, Eva
A1 Pérez de Llano, Luis
A1 Perpiñá, Miguel
A1 Ros, José Antonio
A1 Serrano, José
A1 Soler-Cataluña, Juan José
A1 Torrego, Alfons
A1 Urrutia, Isabel
A1 Plaza, Vicente
K1 Asthma
K1 COPD
K1 Survey
K1 ACOS
K1 Guidelines
K1 Asma
K1 Antiasmáticos
K1 Broncodilatadores
K1 Consenso
K1 Corticoesteroides
K1 Enfermedad pulmonar obstructiva crónica
AB BACKGROUNDSome patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population.MATERIALS AND METHODSWe performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS.RESULTSA total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6% recognized the existence of ACOS and stated that a mean of 12.6% of their patients might have this syndrome. In addition, 80.8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5%), significant smoking exposure (73.1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity <0.7 (69.2%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8%), a very positive bronchodilator test (69.2%), and a history of asthma before 40 years of age (65.4%). Up to 96.2% agreed that first-line treatment for ACOS was the combination of a long-acting β2-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS.CONCLUSIONMost Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting β2-agonist/inhaled corticosteroids.
PB Dove Medical Press
SN 1176-9106
YR 2015
FD 2015-07-15
LK http://hdl.handle.net/10668/2348
UL http://hdl.handle.net/10668/2348
LA en
NO Miravitlles M, Alcázar B, Alvarez FJ, Bazús T, Calle M, Casanova C, et al. What pulmonologists think about the asthma-COPD overlap syndrome. Int J Chron Obstruct Pulmon Dis. 2015; 10:1321-30
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 6, 2025