RT Journal Article T1 Implications of Renal Denervation Therapy in Patients with Sleep Apnea. A1 Jaén-Águila, Fernando A1 Vargas-Hitos, José Antonio A1 Mediavilla-García, Juan Diego K1 Fibrilación atrial K1 Trastornos cerebrovasculares K1 Insuficiencia cardíaca K1 Hipertensión K1 Obesidad K1 Apnea del sueño obstructiva K1 Simpatectomía AB Obstructive sleep apnea (OSA) syndrome is a prevalent condition characterized by repeated episodes of obstruction of the upper airway, leading to intermittent hypoxemia and important endothelial and anatomical dysfunctions that cause cardiovascular and cerebrovascular disease. The finding of the relationship between OSA and hypertension, especially resistant hypertension (RHT), has increased the interest in therapeutic strategies that affect renal sympathetic activity in these patients. The observational studies published until now demonstrated that renal denervation therapy can reduce the severity of OSA syndrome. Renal sympathetic denervation (RDN) could be a future therapeutic possibility for conditions other than RHT, such as atrial fibrillation, heart failure, obesity, and OSA syndrome, where renal sympathetic system plays an important physiological role. The aim of this review was to elucidate the implications of renal sympathetic activity in OSA syndrome. PB Hindawi Publishing Corporation YR 2015 FD 2015 LK http://hdl.handle.net/10668/2381 UL http://hdl.handle.net/10668/2381 LA en NO Jaén-Águila F, Vargas-Hitos JA, Mediavilla-García JD. Implications of Renal Denervation Therapy in Patients with Sleep Apnea. Int J Hypertens. 2015; 2015:408574 NO Journal Article; Review; DS RISalud RD Apr 11, 2025