TY - JOUR AU - Gauthier, Benoit R. AU - Comaills, Valentine PY - 2021 DO - 10.3390/ijms22147281 UR - http://hdl.handle.net/10668/3551 T2 - International Journal of Molecular Sciences AB - The dynamic nature of the nuclear envelope (NE) is often underestimated. The NE protects, regulates, and organizes the eukaryote genome and adapts to epigenetic changes and to its environment. The NE morphology is characterized by a wide range of... LA - en PB - MDPI KW - cGAS/STING KW - Cancer KW - Chromosomal instability KW - Envelopathy KW - Inflammation KW - Lipodystrophy KW - Neuropathy KW - Nuclear envelope KW - Nuclear envelope disruption KW - Neoplasias KW - Inestabilidad cromosómica KW - Inflamación KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Chromosome Aberrations::Chromosomal Instability KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Genomic Instability KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunity::Immunity, Innate KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Cell Membrane::Cell Membrane Structures::Nuclear Envelope TI - Nuclear Envelope Integrity in Health and Disease: Consequences on Genome Instability and Inflammation TY - review article ER -