RT Journal Article T1 Challenges in the Early Diagnosis of Oral Cancer, Evidence Gaps and Strategies for Improvement: A Scoping Review of Systematic Reviews. A1 Gonzalez-Moles, Miguel Angel A1 Aguilar-Ruiz, Manuel A1 Ramos-Garcia, Pablo K1 diagnostic delay K1 early diagnosis K1 meta-analysis K1 oral cancer K1 prognosis K1 scoping review K1 systematic review AB Oral cancer is a growing problem, accounting for 377,713 worldwide new cases per year, and 177,757 deaths annually and representing a 5-year mortality rate close to 50%, which is a considerable mortality that has not decreased substantially in the last 40 years. The main cause of this high mortality is related to the diagnosis of a high percentage of oral cancers in advanced stages (stages III and IV) in which treatment is complex, mutilating or disabling, and ineffective. The essential cause of a cancer diagnosis at a late stage is the delay in diagnosis, therefore, the achievement of the objective of improving the prognosis of oral cancer involves reducing the delay in its diagnosis. The reasons for the delay in the diagnosis of oral cancer are complex and involve several actors and circumstances-patients, health care providers, and health services. In this paper, we present the results of a scoping review of systematic reviews on the diagnostic delay in oral cancer with the aim to better understand, based on the evidence, and discuss in depth, the reasons for this fact, and to identify evidence gaps and formulate strategies for improvement. PB MDPI AG SN 2072-6694 YR 2022 FD 2022-10-08 LK http://hdl.handle.net/10668/20920 UL http://hdl.handle.net/10668/20920 LA en NO González-Moles MÁ, Aguilar-Ruiz M, Ramos-García P. Challenges in the Early Diagnosis of Oral Cancer, Evidence Gaps and Strategies for Improvement: A Scoping Review of Systematic Reviews. Cancers (Basel). 2022 Oct 10;14(19):4967 DS RISalud RD Apr 9, 2025