TY - JOUR AU - Mora-Lorca, José Antonio AU - Sáenz-Narciso, Beatriz AU - Gaffney, Christopher J AU - Naranjo-Galindo, Francisco José AU - Pedrajas, José Rafael AU - Guerrero-Gómez, David AU - Dobrzynska, Agnieszka AU - Askjaer, Peter AU - Szewczyk, Nathaniel J AU - Cabello, Juan AU - Miranda-Vizuete, Antonio PY - 2016 DO - 10.1016/j.freeradbiomed.2016.04.017 UR - http://hdl.handle.net/10668/10024 T2 - Free radical biology & medicine AB - Glutathione is the most abundant thiol in the vast majority of organisms and is maintained in its reduced form by the flavoenzyme glutathione reductase. In this work, we describe the genetic and functional analysis of the Caenorhabditis elegans gsr-1... LA - en KW - Caenorhabditis elegans KW - Embryonic development KW - Glutathione reductase KW - Mitochondria KW - Redox KW - Animals KW - Caenorhabditis elegans KW - Cytoplasm KW - Embryonic Development KW - Genes, Essential KW - Glutathione KW - Glutathione Reductase KW - Mitochondria KW - Mutant Proteins KW - Oxidation-Reduction KW - Protein Isoforms KW - Thioredoxins TI - Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development. TY - research article VL - 96 ER -