TY - JOUR AU - Marquez-Rodas, Ivan AU - Alvarez, Ana AU - Arance, Ana AU - Valduvieco, Izaskun AU - Berciano-Guerrero, Miguel-angel AU - Delgado, Raquel AU - Soria, Ainara AU - Lopez-Campos, Fernando AU - Sanchez, Pedro AU - Romero, Jose Luis AU - Martin-Liberal, Juan AU - Lucas, Anna AU - Diaz-Beveridge, Roberto AU - Conde-Moreno, Antonio-Jose AU - Alamo-de-la-Gala, Maria del Carmen AU - Garcia-Castano, Almudena AU - Prada, Pedro Jose AU - Gonzalez-Cao, Maria AU - Puertas, Enrique AU - Vidal, Joana AU - Foro, Palmira AU - Aguado-de-la-Rosa, Carlos AU - Corona, Juan Antonio AU - Cerezuela-Fuentes, Pablo AU - Lopez, Paco AU - Luna, Pablo AU - Aymar, Neus AU - Puertolas, Teresa AU - Sanagustin, Pilar AU - Berrocal, Alfonso PY - 2024 DO - 10.1093/neuonc/noae116 SN - 1522-8517 UR - https://hdl.handle.net/10668/28507 T2 - Neuro-Oncology AB - Background. Encorafenib plus binimetinib (EB) is a standard-of-care treatment for advanced BRAF(V600)-mutant melanoma. We assessed the efficacy and safety of encorafenib plus binimetinib in patients with BRAF(V600)-mutant melanoma and brain metastasis... LA - en PB - Oxford University Press KW - Brain metastasis KW - Encorafenib and binimetinib KW - Melanoma KW - Radiotherapy KW - Targeted therapy KW - Proto-Oncogene Proteins B-raf KW - Alanine Transaminase KW - Progression-Free Survival KW - Medical Futility KW - Brain Neoplasms KW - Steroids KW - Adrenal Cortex Hormones TI - Encorafenib and binimetinib followed by radiotherapy for patients with BRAFV600-mutant melanoma and brain metastases (E-BRAIN/GEM1802 phase II study) TY - research article VL - 26 ER -