RT Journal Article T1 Compliance with the 2018 World Cancer Research Fund/American Institute for Cancer Research Cancer Prevention Recommendations and Prostate Cancer. A1 Olmedo-Requena, Rocío A1 Lozano-Lorca, Macarena A1 Salcedo-Bellido, Inmaculada A1 Jiménez-Pacheco, Antonio A1 Vázquez-Alonso, Fernando A1 García-Caballos, Marta A1 Sánchez, María-José A1 Jiménez-Moleón, José-JuanJ K1 WCRF/AICR 2018 recommendations K1 case-control study K1 nutrition-based guidelines K1 prostate cancer AB The etiology of prostate cancer (PCa) remains largely unknown. Compliance with the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRC/AICR) cancer prevention recommendations and its relationship to PCa was evaluated. A total of 398 incident PCa cases and 302 controls were included. The selection criteria for both cases and controls were: (i) age between 40-80 years; and (ii) residence in the coverage area of the reference hospitals for 6 months or more prior to recruitment. A score to measure the compliance with the recommendations of 2018 WCRC/AICR criteria was built. The level of compliance was used as a continuous variable and categorized in terciles. The aggressiveness of PCa was determined according to the ISUP classification. Adjusted odds ratios (aOR) and their 95% confidence intervals (95% CI) were estimated using multivariable logistic regression models. A slight protective tendency was observed between the level of compliance with the preventive recommendations and PCa risk, aOR = 0.81 (95% CI 0.69-0.96) for the total cases of PCa. This association also was observed when the aggressiveness was considered. In addition, limiting consumption of "fast foods", sugar-sweetened drinks, and alcohol were independently associated with lower risk of PCa. YR 2020 FD 2020-03-14 LK http://hdl.handle.net/10668/15254 UL http://hdl.handle.net/10668/15254 LA en DS RISalud RD Apr 10, 2025