RT Journal Article
T1 Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response.
A1 Cuesta-Sancho, Sara
A1 Marquez-Coello, Mercedes
A1 Illanes-Alvarez, Francisco
A1 Marquez-Ruiz, Denisse
A1 Arizcorreta, Ana
A1 Galan-Sanchez, Fatima
A1 Montiel, Natalia
A1 Rodriguez-Iglesias, Manuel
A1 Giron-Gonzalez, Jose-Antonio
K1 Cirrhosis decompensation
K1 Direct antiviral agents
K1 Extrahepatic complications
K1 Hepatitis C virus
K1 Hepatocarcinoma
K1 Human immunodeficiency virus
K1 Sustained virological response
AB Loss of follow-up or reinfections hinder the expectations of hepatitis C eradication despite the existence of highly effective treatments. Moreover, the elimination of the infection does not imply the reversion of those chronic alterations derived from the previous infection by hepatitis C virus (HCV). This review analyzes the risk factors associated with loss to follow-up in diagnosis or treatment, and the possibility of reinfection. Likewise, it assesses the residual alterations induced by chronic HCV infection considering the liver alterations (inflammation, fibrosis, risk of decompensation, hepatocellular carcinoma, liver transplantation) and, on the other hand, the comorbidities and extrahepatic manifestations (cryoglobulinemia, non-Hodgkin lymphoma, peripheral insulin resistance, and lipid, bone and cognitive alterations). Peculiarities present in subjects coinfected with human immunodeficiency virus are analyzed in each section.
PB Baishideng Publishing Group
SN 1948-5182
YR 202-
FD 202-12-09
LK http://hdl.handle.net/10668/21634
UL http://hdl.handle.net/10668/21634
LA en
NO Cuesta-Sancho S, Márquez-Coello M, Illanes-Álvarez F, Márquez-Ruiz D, Arizcorreta A, Galán-Sánchez F, et al. Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response. World J Hepatol. 2022 Jan 27;14(1):62-79
DS RISalud
RD Apr 5, 2025