RT Journal Article
T1 Economic evaluation of a guided and unguided internet-based CBT intervention for major depression: Results from a multi-center, three-armed randomized controlled trial conducted in primary care.
A1 Romero-Sanchiz, Pablo
A1 Nogueira-Arjona, Raquel
A1 García-Ruiz, Antonio
A1 Luciano, Juan V
A1 García Campayo, Javier
A1 Gili, Margalida
A1 Botella, Cristina
A1 Baños, Rosa
A1 Castro, Adoración
A1 López-Del-Hoyo, Yolanda
A1 Pérez Ara, Mª Ángeles
A1 Modrego-Alarcón, Marta
A1 Mayoral Cleríes, Fermín
K1 Adulto
K1 Grupos control
K1 Análisis costo-beneficio
K1 Depresión
K1 Trastorno depresivo
K1 Femenino
K1 Estudios de seguimiento
K1 Hispanoamericanos
K1 Humanos
K1 Análisis de intención de tratar
K1 Internet
K1 Atención primaria de salud
K1 Psicoterapia
K1 Sonrisa
K1 Sociedades científicas
AB Depression is one of the most common mental disorders and will become one of the leading causes of disability in the world. Internet-based CBT programs for depression have been classified as "well established" following the American Psychological Association criteria for empirically supported treatments. The aim of this study is to analyze the cost effectiveness at 12-month follow-up of the Internet-based CBT program "Smiling is fun" with (LITG) and without psychotherapist support (TSG) compared to usual care. The perspective used in our analysis is societal. A sample of 296 depressed patients (mean age of 43.04 years; 76% female; BDI-II mean score = 22.37) from primary care services in four Spanish regions were randomized in the RCT. The complete case and intention-to-treat (ITT) perspectives were used for the analyses. The results demonstrated that both Internet-based CBT interventions exhibited cost utility and cost effectiveness compared with a control group. The complete case analyses revealed an incremental cost-effectiveness ratio (ICER) of €-169.50 and an incremental cost-utility ratio (ICUR) of €-11389.66 for the TSG group and an ICER of €-104.63 and an ICUR of €-6380.86 for the LITG group. The ITT analyses found an ICER of €-98.37 and an ICUR of €-5160.40 for the TSG group and an ICER of €-9.91 and an ICUR of €496.72 for the LITG group. In summary, the results of this study indicate that the two Internet-based CBT interventions are appropriate from both economic and clinical perspectives for depressed patients in the Spanish primary care system. These interventions not only help patients to improve clinically but also generate societal savings.
PB Public Libray of Science
YR 2017
FD 2017-02
LK http://hdl.handle.net/10668/2677
UL http://hdl.handle.net/10668/2677
LA en
NO Romero-Sanchiz P, Nogueira-Arjona R, García-Ruiz A, Luciano JV, García Campayo J, Gili M, et al. Economic evaluation of a guided and unguided internet-based CBT intervention for major depression: Results from a multi-center, three-armed randomized controlled trial conducted in primary care. PLoS ONE. 2017; 12(2): e0172741.
NO TRIAL REGISTRATION:clinicaltrials.gov NCT01611818.
DS RISalud
RD Apr 8, 2025