RT Journal Article
T1 The Association of Nighttime Fasting Duration and Prostate Cancer Risk: Results from the Multicase-Control (MCC) Study in Spain.
A1 Palomar-Cros, Anna
A1 Espinosa, Ana
A1 Straif, Kurt
A1 Perez-Gomez, Beatriz
A1 Papantoniou, Kyriaki
A1 Gomez-Acebo, Ines
A1 Molina-Barcelo, Ana
A1 Olmedo-Requena, Rocio
A1 Alguacil, Juan
A1 Fernandez-Tardon, Guillermo
A1 Casabonne, Delphine
A1 Aragones, Nuria
A1 Castaño-Vinyals, Gemma
A1 Pollan, Marina
A1 Romaguera, Dora
A1 Kogevinas, Manolis
K1 breakfast
K1 chrononutrition
K1 circadian rhythms
K1 early time-restricted feeding
K1 prolonged nighttime fasting
K1 prostate cancer
AB Nighttime fasting has been inconclusively associated with a reduced risk of cancer. The purpose of this study was to investigate this association in relation to prostate cancer risk. We examined data from 607 prostate cancer cases and 848 population controls who had never worked in night shift work from the Spanish multicase-control (MCC) study, 2008-2013. Through an interview, we collected circadian information on meal timing at mid-age. We estimated odds ratios (OR) and 95% confidence intervals (CI) with unconditional logistic regression. After controlling for time of breakfast, fasting for more than 11 h overnight (the median duration among controls) was associated with a reduced risk of prostate cancer compared to those fasting for 11 h or less (OR = 0.77, 95% 0.54-1.07). Combining a long nighttime fasting and an early breakfast was associated with a lower risk of prostate cancer compared to a short nighttime fasting and a late breakfast (OR = 0.54, 95% CI 0.27-1.04). This study suggests that a prolonged nighttime fasting duration and an early breakfast may be associated with a lower risk of prostate cancer. Findings should be interpreted cautiously and add to growing evidence on the importance of chrononutrition in relation to cancer risk.
PB MDPI AG
YR 2021
FD 2021-07-30
LK http://hdl.handle.net/10668/18454
UL http://hdl.handle.net/10668/18454
LA en
NO Palomar-Cros A, Espinosa A, Straif K, Pérez-Gómez B, Papantoniou K, Gómez-Acebo I, et al. The Association of Nighttime Fasting Duration and Prostate Cancer Risk: Results from the Multicase-Control (MCC) Study in Spain. Nutrients. 2021 Jul 30;13(8):2662.
DS RISalud
RD Apr 20, 2025