TY  - JOUR
AU  - Fernandez, Ana M
AU  - Martinez-Rachadell, Laura
AU  - Navarrete, Marta
AU  - Pose-Utrilla, Julia
AU  - Davila, Jose Carlos
AU  - Pignatelli, Jaime
AU  - Diaz-Pacheco, Sonia
AU  - Guerra-Cantera, Santiago
AU  - Viedma-Moreno, Emilia
AU  - Palenzuela, Rocio
AU  - Ruiz de Martin Esteban, Samuel
AU  - Mostany, Ricardo
AU  - Garcia-Caceres, Cristina
AU  - Tschöp, Matthias
AU  - Iglesias, Teresa
AU  - de Ceballos, Maria L
AU  - Gutierrez, Antonia
AU  - Torres Aleman, Ignacio
PY  - 2022
DO  - 10.1073/pnas.2204527119
UR  - http://hdl.handle.net/10668/19668
T2  - Proceedings of the National Academy of Sciences of the United States of America
AB  - Mice with insulin receptor (IR)-deficient astrocytes (GFAP-IR knockout [KO] mice) show blunted responses to insulin and reduced brain glucose uptake, whereas IR-deficient astrocytes show disturbed mitochondrial responses to glucose. While exploring...
LA  - en
KW  - astrocytes
KW  - insulin
KW  - neurovascular coupling
KW  - Animals
KW  - Astrocytes
KW  - Brain
KW  - Glial Fibrillary Acidic Protein
KW  - Glucose
KW  - Insulin
KW  - Mice
KW  - Mice, Knockout
KW  - Neovascularization, Physiologic
KW  - Neurovascular Coupling
KW  - Reactive Oxygen Species
KW  - Receptor, Insulin
KW  - Vascular Endothelial Growth Factor A
TI  - Insulin regulates neurovascular coupling through astrocytes.
TY  - research article
VL  - 119
ER  -