TY - JOUR AU - Mancikova, Veronika AU - Montero-Conde, Cristina AU - Perales-Paton, Javier AU - Fernandez, Agustin AU - Santacana, María AU - Jodkowska, Karolina AU - Inglada-Pérez, Lucia AU - Castelblanco, Esmeralda AU - Borrego, Salud AU - Encinas, Mario AU - Matias-Guiu, Xavier AU - Fraga, Mario AU - Robledo, Mercedes PY - 2016 DO - 10.1158/1078-0432.CCR-16-0947 UR - http://hdl.handle.net/10668/10437 T2 - Clinical cancer research : an official journal of the American Association for Cancer Research AB - Purpose: Medullary thyroid carcinoma (MTC) is a rare disease with few genetic drivers, and the etiology specific to each known susceptibility mutation remains unknown. Exploiting multilayer genomic data, we focused our interest on the role of aberrant... LA - en KW - Carcinoma, Neuroendocrine KW - DNA Methylation KW - Female KW - Gene Expression Regulation, Neoplastic KW - Genome, Human KW - Genomics KW - Humans KW - Male KW - Mutation KW - Piperidines KW - Proto-Oncogene Proteins c-ret KW - Quinazolines KW - STAT3 Transcription Factor KW - Signal Transduction KW - Thyroid Neoplasms TI - Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors. TY - research article VL - 23 ER -