TY - JOUR AU - Fernández-Ortiz, Marisol AU - Sayed, Ramy K.A. AU - Fernández-Martínez, José AU - Cionfrini, Antonia AU - Aranda-Martínez, Paula AU - Escames, Germaine AU - de Haro, Tomás AU - Acuña-Castroviejo, Darío PY - 2020 DO - 10.3390/antiox9121187 UR - http://hdl.handle.net/10668/3654 T2 - Antioxidants AB - Aging is a major risk for cardiovascular diseases (CVD). Age-related disorders include oxidative stress, mitochondria dysfunction, and exacerbation of the NF-κB/NLRP3 innate immune response pathways. Some of the molecular mechanisms underlying these... LA - en PB - MDPI KW - Melatonin KW - Mitochondria KW - NLRP3 inflammasome KW - Nrf2 KW - Heart ultrastructure KW - Apoptosis KW - Mitochondrial dynamics KW - Melatonina KW - Mitocondria KW - Corazón KW - Inflamasomas KW - Factor 2 Relacionado con NF-E2 KW - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Melatonin KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Subcellular Fractions::Mitochondria KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::Inflammasomes KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic-Leucine Zipper Transcription Factors::NF-E2-Related Factor 2 KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants KW - Medical Subject Headings::Diseases::Cardiovascular Diseases KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Autophagy KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Aging KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Stress, Physiological::Oxidative Stress TI - Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging TY - research article ER -