TY  - JOUR
AU  - Serran-Aguilera, Lucia
AU  - Denton, Helen
AU  - Rubio-Ruiz, Belen
AU  - Lopez-Gutierrez, Borja
AU  - Entrena, Antonio
AU  - Izquierdo, Luis
AU  - Smith, Terry K
AU  - Conejo-Garcia, Ana
AU  - Hurtado-Guerrero, Ramon
PY  - 2016
DO  - 10.1038/srep33189
UR  - http://hdl.handle.net/10668/10432
T2  - Scientific reports
AB  - Malaria is a life-threatening disease caused by different species of the protozoan parasite Plasmodium, with P. falciparum being the deadliest. Increasing parasitic resistance to existing antimalarials makes the necessity of novel avenues to treat...
LA  - en
PB  - Nature Publishing Group
KW  - Lipids
KW  - Infectious diseases
KW  - Phosphatidylethanolamines
KW  - Protozoan Proteins
KW  - Cells, Cultured
KW  - Erythrocytes
KW  - Antimalarials
KW  - Catalytic Domain
KW  - Choline Kinase
KW  - Crystallography, X-Ray
KW  - Drug Evaluation, Preclinical
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Kinetics
KW  - Models, Molecular
KW  - Plasmodium falciparum
KW  - Protein Binding
KW  - Trophozoites
TI  - Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death.
TY  - research article
VL  - 6
ER  -