TY - JOUR AU - Abáigar, María AU - Robledo, Cristina AU - Benito, Rocío AU - Ramos, Fernando AU - Díez-Campelo, María AU - Hermosín, Lourdes AU - Sánchez-Del-Real, Javier AU - Alonso, Jose M AU - Cuello, Rebeca AU - Megido, Marta AU - Rodríguez, Juan N AU - Martín-Núñez, Guillermo AU - Aguilar, Carlos AU - Vargas, Manuel AU - Martín, Ana A AU - García, Juan L AU - Kohlmann, Alexander AU - Del Cañizo, M Consuelo AU - Hernández-Rivas, Jesús M PY - 2016 DO - 10.1371/journal.pone.0164370 UR - http://hdl.handle.net/10668/10536 T2 - PloS one AB - To explore novel genetic abnormalities occurring in myelodysplastic syndromes (MDS) through an integrative study combining array-based comparative genomic hybridization (aCGH) and next-generation sequencing (NGS) in a series of MDS and... LA - en KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Child KW - Chromosome Aberrations KW - Chromosomes, Human, Pair 13 KW - Comparative Genomic Hybridization KW - Core Binding Factor Alpha 2 Subunit KW - DNA KW - DNA (Cytosine-5-)-Methyltransferases KW - DNA Copy Number Variations KW - DNA Methyltransferase 3A KW - DNA Mutational Analysis KW - DNA-Binding Proteins KW - Dioxygenases KW - Female KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Karyotype KW - Male KW - Middle Aged KW - Myelodysplastic Syndromes KW - Proto-Oncogene Proteins KW - Recurrence KW - Risk KW - Tumor Suppressor Protein p53 KW - Young Adult TI - Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes. TY - research article VL - 11 ER -