TY - JOUR AU - Ortiz-Aljaro, Pilar AU - Montes-Cano, Marco Antonio AU - García-Lozano, José-Raúl AU - Aquino, Virginia AU - Carmona, Rosario AU - Perez-Florido, Javier AU - García-Hernández, Francisco José AU - Dopazo, Joaquín AU - González-Escribano, María Francisca PY - 2022 DO - 10.1038/s41598-022-15549-0 UR - http://hdl.handle.net/10668/19615 T2 - Scientific reports AB - Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease. Belimumab, a monoclonal antibody targets BAFF, is the only biologic approved for SLE and active lupus nephritis. BAFF is a cytokine with a key-regulatory role in the B cell... LA - en KW - Adolescent KW - Adult KW - B-Cell Activating Factor KW - B-Cell Maturation Antigen KW - Case-Control Studies KW - Female KW - Humans KW - Lupus Erythematosus, Systemic KW - Lupus Nephritis KW - Middle Aged KW - Protein Isoforms KW - Tumor Necrosis Factor Ligand Superfamily Member 13 KW - Young Adult TI - Protein and functional isoform levels and genetic variants of the BAFF and APRIL pathway components in systemic lupus erythematosus. TY - research article VL - 12 ER -