TY  - JOUR
AU  - Pérez-Arana, Gonzalo
AU  - Blandino-Rosano, Manuel
AU  - Prada-Oliveira, Arturo
AU  - Aguilar-Diosdado, Manuel
AU  - Segundo, Carmen
PY  - 2010
DO  - 10.1210/en.2009-1113
SN  - 0013-7227
UR  - http://hdl.handle.net/10668/727
T2  - Endocrinology
AB  - In autoimmune type 1 diabetes mellitus, proinflammatory cytokine-mediated apoptosis of beta-cells has been considered to be the first event directly responsible for beta-cell mass reduction. In the Bio-Breeding (BB) rat, an in vivo model used in the...
LA  - en
PB  - Endocrine Society
KW  - Agentes hipoglucémicos
KW  - Péptidos
KW  - Veneno
KW  - Exenatida
KW  - Interferon-gamma
KW  - Diabetes Mellitus
KW  - Anticuerpos
KW  - Animales
KW  - Ratas Wistar
KW  - Distribución aleatoria
KW  - Células secretoras de insulina
KW  - Inmunohistoquímica
KW  - Test de tolerancia a la glucosa
KW  - Péptido glucagonoide 1
KW  - Proliferación celular
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 1
KW  - Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Gastrointestinal Hormones::Proglucagon::Glucagon-Like Peptides::Glucagon-Like Peptide 1
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Clinical Chemistry Tests::Blood Chemical Analysis::Glucose Tolerance Test
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunohistochemistry
KW  - Medical Subject Headings::Anatomy::Endocrine System::Enteroendocrine Cells::Insulin-Secreting Cells
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interferons::Interferon-gamma
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Random Allocation
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Wistar
KW  - Medical Subject Headings::Anatomy::Fluids and Secretions::Bodily Secretions::Venoms
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
TI  - Decrease in beta-Cell Proliferation Precedes Apoptosis during Diabetes Development in Bio-Breeding/Worcester Rat: Beneficial Role of Exendin-4
TY  - research article
ER  -