TY  - JOUR
AU  - Lopez-Cortes, Luis Eduardo
AU  - Rosso-Fernandez, Clara
AU  - Nuñez-Nuñez, Maria
AU  - Lavin-Alconero, Lucia
AU  - Bravo-Ferrer, Jose
AU  - Barriga, Angel
AU  - Delgado, Mercedes
AU  - Lupion, Carmen
AU  - Retamar, Pilar
AU  - Rodriguez-Baño, Jesus
PY  - 2017
DO  - 10.1136/bmjopen-2016-015439
UR  - http://hdl.handle.net/10668/11292
T2  - BMJ open
AB  - Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one of the proposed strategies for reducing the unnecessary use of broad-spectrum antibiotics (BSA). The empirical treatment of nosocomial and some...
LA  - en
PB  - BMJ Group
KW  - Enterobacteriaceae
KW  - De-escalation
KW  - antimicrobial stewardship
KW  - bloodstream infection
KW  - broad-spectrum antibiotics
KW  - Anti-Bacterial Agents
KW  - Bacteremia
KW  - Drug Administration Routes
KW  - Enterobacteriaceae
KW  - Enterobacteriaceae Infections
KW  - Humans
KW  - Microbial Sensitivity Tests
KW  - Pseudomonas
KW  - Pseudomonas Infections
KW  - Research Design
KW  - Treatment Outcome
KW  - beta-Lactams
TI  - Targeted simplification versus antipseudomonal broad-spectrum beta-lactams in patients with bloodstream infections due to Enterobacteriaceae (SIMPLIFY): a study protocol for a multicentre, open-label, phase III randomised, controlled, non-inferiority clinical trial.
TY  - research article
VL  - 7
ER  -