TY  - JOUR
AU  - Pajares, Maria A
AU  - Zimmerman, Tahl
AU  - Sanchez-Gomez, Francisco J
AU  - Ariza, Adriana
AU  - Torres, Maria J
AU  - Blanca, Miguel
AU  - Cañada, F Javier
AU  - Montañez, Maria I
AU  - Perez-Sala, Dolores
PY  - 2020
DO  - 10.3389/fphar.2020.00189
SN  - 1663-9812
UR  - https://hdl.handle.net/10668/26837
T2  - Frontiers in pharmacology
AB  - Serum and cellular proteins are targets for the formation of adducts with the β-lactam antibiotic amoxicillin. This process could be important for the development of adverse, and in particular, allergic reactions to this antibiotic. In studies...
LA  - en
PB  - Frontiers Research Foundation
KW  - Amoxicillin
KW  - Bacterial growth
KW  - Inactivation mechanism
KW  - Protein adducts
KW  - Redox regulation
KW  - Thiol groups
KW  - Thiol-containing molecules
KW  - β-lactam antibiotics
KW  - Serum Albumin, Human
KW  - Ampicillin
KW  - Oxidation-Reduction
KW  - Penicillin G
KW  - Hypersensitivity
KW  - Glutathione
TI  - Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency.
TY  - research article
VL  - 11
ER  -