TY  - JOUR
AU  - Dominguez-Gonzalez, Cristina
AU  - Badosa, Carmen
AU  - Madruga-Garrido, Marcos
AU  - Martí, Itxaso
AU  - Paradas, Carmen
AU  - Ortez, Carlos
AU  - Diaz-Manera, Jordi
AU  - Berardo, Andres
AU  - Alonso-Pérez, Jorge
AU  - Trifunov, Selena
AU  - Cuadras, Daniel
AU  - Kalko, Susana G
AU  - Blázquez-Bermejo, Cora
AU  - Cámara, Yolanda
AU  - Martí, Ramon
AU  - Mavillard, Fabiola
AU  - Martin, Miguel A
AU  - Montoya, Julio
AU  - Ruiz-Pesini, Eduardo
AU  - Villarroya, Joan
AU  - Montero, Raquel
AU  - Villarroya, Francesc
AU  - Artuch, Rafael
AU  - Hirano, Michio
AU  - Nascimento, Andrés
AU  - Jimenez-Mallebrera, Cecilia
PY  - 2020
DO  - 10.1038/s41598-020-66940-8
UR  - http://hdl.handle.net/10668/15798
T2  - Scientific reports
AB  - GDF-15 is a biomarker for mitochondrial diseases. We investigated the application of GDF-15 as biomarker of disease severity and response to deoxynucleoside treatment in patients with thymidine kinase 2 (TK2) deficiency and compared it to FGF-21....
LA  - en
KW  - Adult
KW  - Aged
KW  - Biomarkers
KW  - Child
KW  - Child, Preschool
KW  - DNA, Mitochondrial
KW  - Female
KW  - Fibroblast Growth Factors
KW  - Growth Differentiation Factor 15
KW  - Humans
KW  - Infant
KW  - Male
KW  - Middle Aged
KW  - Mitochondrial Diseases
KW  - Muscle, Skeletal
KW  - Muscular Diseases
KW  - Prognosis
KW  - Thymidine Kinase
TI  - Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy.
TY  - research article
VL  - 10
ER  -