TY  - JOUR
AU  - Rodríguez-Agudo, Rubén
AU  - Goikoetxea-Usandizaga, Naroa
AU  - Serrano-Maciá, Marina
AU  - Fernández-Tussy, Pablo
AU  - Fernández-Ramos, David
AU  - Lachiondo-Ortega, Sofía
AU  - González-Recio, Irene
AU  - Gil-Pitarch, Clàudia
AU  - Mercado-Gómez, María
AU  - Morán, Laura
AU  - Bizkarguenaga, Maider
AU  - Lopitz-Otsoa, Fernando
AU  - Petrov, Petar
AU  - Bravo, Miren
AU  - Van Liempd, Sebastiaan Martijn
AU  - Falcon-Perez, Juan Manuel
AU  - Zabala-Letona, Amaia
AU  - Carracedo, Arkaitz
AU  - Castell, Jose Vicente
AU  - Jover, Ramiro
AU  - Martínez-Cruz, Luis Alfonso
AU  - Delgado, Teresa Cardoso
AU  - Cubero, Francisco Javier
AU  - Lucena, María Isabel
AU  - Andrade, Raúl Jesús
AU  - Mabe, Jon
AU  - Simón, Jorge
AU  - Martínez-Chantar, María Luz
PY  - 2022
DO  - 10.3390/antiox11050897
SN  - 2076-3921
UR  - http://hdl.handle.net/10668/20781
T2  - Antioxidants (Basel, Switzerland)
AB  - Drug-induced liver injury (DILI) development is commonly associated with acetaminophen (APAP) overdose, where glutathione scavenging leads to mitochondrial dysfunction and hepatocyte death. DILI is a severe disorder without effective late-stage...
LA  - en
KW  - acetaminophen (APAP)
KW  - ammonia
KW  - drug-induced liver injury (DILI)
KW  - methionine cycle
KW  - miR-873-5p
KW  - mitochondria
KW  - polyamines
KW  - therapy
TI  - Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen.
TY  - research article
VL  - 11
ER  -