TY - JOUR AU - López-Rodríguez, Rosario AU - Hernández-Bartolomé, Ángel AU - Borque, María Jesús AU - Rodríguez-Muñoz, Yolanda AU - Martín-Vílchez, Samuel AU - García-Buey, Luisa AU - González-Moreno, Leticia AU - Real-Martínez, Yolanda AU - Muñoz de Rueda, Paloma AU - Salmerón, Javier AU - Vidal-Castiñeira, José Ramón AU - López-Larrea, Carlos AU - Rodrigo, Luis AU - Moreno-Otero, Ricardo AU - Sanz-Cameno, Paloma PY - 2017 DO - 10.1371/journal.pone.0180927 UR - http://hdl.handle.net/10668/11403 T2 - PloS one AB - Chronic hepatitis C (CHC) is a major cause of liver disease worldwide which often leads to progressive liver inflammation, fibrosis, cirrhosis and hepatocellular carcinoma (HCC). CHC displays heterogeneous progression depending on a broad set of... LA - en KW - 2',5'-Oligoadenylate Synthetase KW - Adult KW - Aged KW - Aspartate Aminotransferases KW - Endoribonucleases KW - Female KW - Hepatitis C, Chronic KW - Humans KW - Interferons KW - Interleukins KW - Janus Kinase 1 KW - Male KW - Middle Aged KW - Polymorphism, Single Nucleotide KW - Suppressor of Cytokine Signaling 1 Protein KW - TYK2 Kinase TI - Interferon-related genetic markers of necroinflammatory activity in chronic hepatitis C. TY - research article VL - 12 ER -