TY  - JOUR
AU  - Lorenzo, Petra I.
AU  - Cobo-Vuilleumier, Nadia
AU  - Martín-Vázquez, Eugenia
AU  - López-Noriega, Livia
AU  - Gauthier, Benoit R.
PY  - 2021
DO  - 10.3390/ijms22084239
UR  - http://hdl.handle.net/10668/3670
T2  - International Journal of Molecular Sciences
AB  - Diabetes is a chronic metabolic disease caused by an absolute or relative deficiency in functional pancreatic β-cells that leads to defective control of blood glucose. Current treatments for diabetes, despite their great beneficial effects on clinical...
LA  - en
PB  - MDPI
KW  - Diabetes
KW  - Regeneration
KW  - β-cell heterogeneity
KW  - Transdifferentiation
KW  - Redifferentiation
KW  - Singlecell transcriptomics
KW  - PAX4
KW  - LRH-1/NR52A
KW  - HMG20A
KW  - Diabetes mellitus
KW  - Regeneración
KW  - Transdiferenciación
KW  - Células secretoras de insulina
KW  - Homeostasis
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Transdifferentiation
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 1
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins
KW  - Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Regenerative Medicine
KW  - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose::Blood Glucose
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Transcription, Genetic::Transcriptome
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Transdifferentiation
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
KW  - Medical Subject Headings::Anatomy::Endocrine System::Enteroendocrine Cells::Insulin-Secreting Cells
TI  - Harnessing the Endogenous Plasticity of Pancreatic Islets: A Feasible Regenerative Medicine Therapy for Diabetes?
TY  - review article
ER  -