TY - JOUR AU - Ponde, Noam AU - Bradbury, Ian AU - Lambertini, Matteo AU - Ewer, Michael AU - Campbell, Christine AU - Ameels, Helene AU - Zardavas, Dimitrios AU - Di Cosimo, Serena AU - Baselga, José AU - Huober, Jens AU - Izquierdo, Miguel AU - Fumagalli, Debora AU - Bozovic-Spasojevic, Ivana AU - Maetens, Marion AU - Harbeck, Nadia AU - Pusztai, Lajos AU - Berghorn, Michael AU - Im, Young-Hyuck AU - Borrego, Manuel Ruiz AU - Chen, Dar-Ren AU - Rodeheffer, Richard AU - Piccart, Martine AU - Suter, Thomas AU - de Azambuja, Evandro PY - 2017 DO - 10.1007/s10549-017-4628-3 UR - http://hdl.handle.net/10668/11951 T2 - Breast cancer research and treatment AB - Biomarkers of cardiac damages, such as troponin T (TnT) and the amino-terminal fragment of brain natriuretic peptide (NT-proBNP), may be useful as early predictors of cardiac dysfunction. The role of these biomarkers in patients receiving lapatinib... LA - en KW - Brain natriuretic peptide KW - Cardiotoxicity KW - HER2 positive breast cancer KW - Lapatinib KW - Troponin T KW - Aged KW - Biomarkers KW - Breast Neoplasms KW - Cardiotoxicity KW - Cardiovascular Abnormalities KW - Drug-Related Side Effects and Adverse Reactions KW - Female KW - Humans KW - Lapatinib KW - Middle Aged KW - Natriuretic Peptide, Brain KW - Neoplasm Staging KW - Paclitaxel KW - Receptor, ErbB-2 KW - Trastuzumab KW - Troponin T TI - Cardiac biomarkers for early detection and prediction of trastuzumab and/or lapatinib-induced cardiotoxicity in patients with HER2-positive early-stage breast cancer: a NeoALTTO sub-study (BIG 1-06). TY - research article VL - 168 ER -