TY - JOUR AU - Lotta, Luca A AU - Sharp, Stephen J AU - Burgess, Stephen AU - Perry, John R B AU - Stewart, Isobel D AU - Willems, Sara M AU - Luan, Jian'an AU - Ardanaz, Eva AU - Arriola, Larraitz AU - Balkau, Beverley AU - Boeing, Heiner AU - Deloukas, Panos AU - Forouhi, Nita G AU - Franks, Paul W AU - Grioni, Sara AU - Kaaks, Rudolf AU - Key, Timothy J AU - Navarro, Carmen AU - Nilsson, Peter M AU - Overvad, Kim AU - Palli, Domenico AU - Panico, Salvatore AU - Quirós, Jose-Ramón AU - Riboli, Elio AU - Rolandsson, Olov AU - Sacerdote, Carlotta AU - Salamanca, Elena C AU - Slimani, Nadia AU - Spijkerman, Annemieke Mw AU - Tjonneland, Anne AU - Tumino, Rosario AU - van der A, Daphne L AU - van der Schouw, Yvonne T AU - McCarthy, Mark I AU - Barroso, Inês AU - O'Rahilly, Stephen AU - Savage, David B AU - Sattar, Naveed AU - Langenberg, Claudia AU - Scott, Robert A AU - Wareham, Nicholas J PY - 2016 DO - 10.1001/jama.2016.14568 UR - http://hdl.handle.net/10668/10502 T2 - JAMA AB - Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs.... LA - en KW - ATP Binding Cassette Transporter, Subfamily G, Member 5 KW - Adult KW - Aged KW - Cholesterol, LDL KW - Cohort Studies KW - Coronary Artery Disease KW - Diabetes Mellitus, Type 2 KW - Drug Therapy, Combination KW - Ezetimibe KW - Genetic Association Studies KW - Genetic Variation KW - Humans KW - Hydroxymethylglutaryl CoA Reductases KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Lipoproteins KW - Membrane Proteins KW - Membrane Transport Proteins KW - Middle Aged KW - Odds Ratio KW - Polymorphism, Genetic KW - Proprotein Convertase 9 KW - Receptors, LDL KW - Risk KW - Simvastatin TI - Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis. TY - research article VL - 316 ER -