TY  - JOUR
AU  - de los Santos-Jiménez, Juan
AU  - Campos-Sandoval, José A.
AU  - Márquez-Torres, Clara
AU  - Urbano-Polo, Nieves
AU  - Brøndegaard, David
AU  - Martín-Rufián, Mercedes
AU  - Lobo, Carolina
AU  - Peñalver, Ana
AU  - Gómez-García, María C.
AU  - Martín-Campos, Janet
AU  - Cardona, Carolina
AU  - Castilla, Laura
AU  - da Costa Souza, Felipe
AU  - Cheng, Tzuling
AU  - Segura, Juan A.
AU  - Alonso, Francisco J.
AU  - Curi, Rui
AU  - Colquhoun, Alison
AU  - DeBerardinis, Ralph J.
AU  - Márquez, Javier
AU  - Matés, José M.
PY  - 2021
DO  - 10.1186/s12929-021-00712-y
SN  - 1021-7770
UR  - http://hdl.handle.net/10668/4511
T2  - Journal of Biomedical Science
AB  - BackgroundGlutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs) have been implicated in progression...
LA  - en
PB  - BioMed Central, Springer Nature
KW  - Antioxidant enzymes
KW  - Cancer
KW  - Glioblastoma
KW  - Glutaminase
KW  - MicroRNA
KW  - Oxidative stress
KW  - Cell line
KW  - Lipid peroxidation
KW  - Glutathione
KW  - Isoenzymes
KW  - Antioxidantes
KW  - Enzimas
KW  - Neoplasias
KW  - Glutaminasa
KW  - MicroARNs
KW  - Estrés oxidativo
KW  - Línea celular
KW  - Peroxidación de lípido
KW  - Glutatión
KW  - Isoenzimas
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neoplasms, Neuroepithelial::Glioma::Astrocytoma::Glioblastoma
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases::Glutaminase
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Isoenzymes
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Antisense Elements (Genetics)::RNA, Antisense::MicroRNAs
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on Sulfur Group Donors::Glutathione Reductase
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Lipid Peroxidation
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Protein Carbonylation
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes
KW  - Medical Subject Headings::Diseases::Neoplasms
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Isoforms
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
TI  - Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells
TY  - research article
ER  -