RT Generic
T1 Impact of Psoriasis and Hidradenitis Suppurativa in Pregnancy, a Systematic Review
A1 Ferrer-Alcala, Maria-Angeles
A1 Sanchez-Diaz, Manuel
A1 Arias-Santiago, Salvador
A1 Molina-Leyva, Alejandro
K1 hidradenitis suppurativa
K1 psoriasis
K1 pregnancy
K1 Generalized pustular psoriasis
K1 Quality-of-life
K1 Natural-history
K1 Male-fertility
K1 Case series
K1 Women
K1 Outcomes
K1 Prevalence
K1 Arthritis
K1 Disease
AB Psoriasis and hidradenitis suppurativa (HS) are chronic inflammatory skin diseases that frequently develop in young women. The aim of this study is to evaluate how hidradenitis suppurativa and psoriasis impact women desiring to conceive, and their influence on fertility and gestation. A systematic review of articles dating from January 2015 to April 2021 was performed using the Scopus (Elsevier) database. The search terms were (psoriasis and (birth or pregnancy or fertility)) and ((hidradenitis suppurativa or acne inversa) and (birth or pregnancy or fertility)). The search was limited to human data. Systematic reviews, case reports, clinical practice guidelines, expert consensus and conference papers were excluded. The impact of HS on pregnancy includes an impaired desire for pregnancy, a decrease in fertility, the worsening of the disease during pregnancy and potential adverse events during pregnancy. Moreover, the pregnancy might imply a change on the treatment of HS. The impact of psoriasis on pregnancy includes a decrease in fertility, potential adverse events during pregnancy and an unpredictable evolution of the disease. Moreover, the pregnancy might imply a change on the treatment of psoriasis, although biologic therapies do not appear to increase the risk of adverse events. In conclusion, both HS and psoriasis have an impact on pregnancy. A decrease of fertility has been reported. Moreover, both diseases have an unpredictable evolution during pregnancy. Pregnant women who are under biologic therapy do not seem to have a higher rate of adverse events. Treatment of both conditions is usually halted during pregnancy since scientific evidence about their safety is not conclusive, or teratogenic risk has been proven.
PB Mdpi
YR 2021
FD 2021-12-01
LK https://hdl.handle.net/10668/26437
UL https://hdl.handle.net/10668/26437
LA en
DS RISalud
RD Apr 12, 2025