TY  - JOUR
AU  - McElroy, Gregory S
AU  - Chakrabarty, Ram P
AU  - D'Alessandro, Karis B
AU  - Hu, Yuan-Shih
AU  - Vasan, Karthik
AU  - Tan, Jerica
AU  - Stoolman, Joshua S
AU  - Weinberg, Samuel E
AU  - Steinert, Elizabeth M
AU  - Reyfman, Paul A
AU  - Singer, Benjamin D
AU  - Ladiges, Warren C
AU  - Gao, Lin
AU  - Lopéz-Barneo, José
AU  - Ridge, Karen
AU  - Budinger, G R Scott
AU  - Chandel, Navdeep S
PY  - 2022
DO  - 10.1038/s41598-022-09074-3
UR  - http://hdl.handle.net/10668/19595
T2  - Scientific reports
AB  - Aging in mammals leads to reduction in genes encoding the 45-subunit mitochondrial electron transport chain complex I. It has been hypothesized that normal aging and age-related diseases such as Parkinson's disease are in part due to modest decrease...
LA  - en
KW  - Animals
KW  - Electron Transport Complex I
KW  - Mammals
KW  - Metformin
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mitochondria
KW  - NADH Dehydrogenase
KW  - RNA, Messenger
TI  - Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.
TY  - research article
VL  - 12
ER  -