RT Journal Article
T1 Prepregnancy body mass index influences lipid oxidation rate during pregnancy.
A1 Bugatto, Fernando
A1 Quintero-Prado, Rocío
A1 Vilar-Sánchez, José M
A1 Perdomo, Germán
A1 Torrejón, Rafael
A1 Bartha, José L
K1 Energy metabolism
K1 indirect calorimetry
K1 lipid oxidation
K1 overweight
K1 pregnancy
K1 respiratory quotient
AB The influence of maternal body mass index (BMI) on respiratory quotient during pregnancy is not clear. We aim to evaluate longitudinal changes in energy expenditure, respiratory quotient, and substrate oxidation rates in normal and overweight women with uncomplicated pregnancies. We hypothesized that the threshold period in switching from a predominantly carbohydrate to a predominantly lipid metabolism may be different in normal and overweight women. Forty healthy pregnant women were recruited for a prospective cohort study. They were divided into two groups, normal and overweight (BMI  There was a significant increase in oxygen consumption (Vo2 ), carbon dioxide production (Vco2 ) and resting energy expenditure during pregnancy in both normal and overweight women. In the normal weight group, respiratory quotient decreased during the second trimester and increased in the last trimester. Respiratory quotient was lower in the overweight group in the second trimester and decreased in the last trimester; between-group differences being significant at 20 and 36 weeks (0.85 ± 0.06 vs. 0.81 ± 0.01, p = 0.009; 0.87 ± 0.05 vs. 0.80 ± 0.03, p = 0.01, respectively). Lipid oxidation was significantly higher in overweight women at both 20 and 36 weeks (36.8 ± 19.7% vs. 55.2 ± 5.6%, p = 0.003 and 33.6 ± 18.2% vs. 59.6 ± 12.7%, p = 0.007, for normal and overweight group, respectively). Prepregnancy maternal BMI influences lipid oxidation rate and respiratory quotient during pregnancy.
YR 2016
FD 2016-12-20
LK http://hdl.handle.net/10668/10615
UL http://hdl.handle.net/10668/10615
LA en
DS RISalud
RD Apr 4, 2025