TY - JOUR AU - Saliba, Soraya Wilke AU - Marcotegui, Ariel R AU - Fortwängler, Ellen AU - Ditrich, Johannes AU - Perazzo, Juan Carlos AU - Muñoz, Eduardo AU - de Oliveira, Antônio Carlos Pinheiro AU - Fiebich, Bernd L PY - 2017 DO - 10.1186/s12974-017-1014-3 UR - http://hdl.handle.net/10668/11903 T2 - Journal of neuroinflammation AB - N-arachidonoylphenolamine (AM404), a paracetamol metabolite, is a potent agonist of the transient receptor potential vanilloid type 1 (TRPV1) and low-affinity ligand of the cannabinoid receptor type 1 (CB1). There is evidence that AM404 exerts its... LA - en PB - BioMed Central KW - AM404 KW - Acetaminophen KW - Cyclooxygenase KW - Inflammation KW - Microglia KW - Prostaglandins KW - Acetaminophen KW - Animals KW - Anti-inflammatory agents KW - Arachidonic acids KW - Cells, cultured KW - Cyclooxygenase 1 KW - Cyclooxygenase 2 KW - Cyclooxygenase inhibitors KW - Mice KW - Mice, inbred C57BL KW - Microglia KW - Prostaglandins KW - Rats KW - Rats, Sprague-Dawley TI - AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity. TY - research article VL - 14 ER -