RT Generic
T1 The Influence of Diet and Probiotics on the Response of Solid Tumours to Immunotherapy: Present and Future Perspectives
A1 Olivares-Hernandez, Alejandro
A1 Figuero-Perez, Luis
A1 Gonzalez-Sarmiento, Rogelio
A1 Leon-Jimenez, David
A1 Jesus Cruz-Hernandez, Juan
A1 Pablo Miramontes-Gonzalez, Jose
K1 diet
K1 probiotics
K1 immunotherapy
K1 solid tumours
K1 Colorectal-cancer
K1 Gut microbiota
K1 Obesity
K1 Ctla-4
K1 Target
K1 Fiber
AB Currently, various immunotherapeutic treatments are revolutionizing therapies that treat solid neoplasms. For these treatments, within immunotherapy, immune checkpoint inhibitors (ICIs) are the most widely used drugs. Diverse studies have shown the influence of diet and probiotics on the response to ICIs and consequently on the survival rates associated with different neoplasms. The use of various antibiotics, probiotics, and prebiotics has been associated with changes in the gut microbiota, and this, in turn, with resistance to immunotherapy. Together with the above, a lower intake of red meat and greater consumption of a Mediterranean, vegetarian, or vegan diet have led to a new way of understanding the mechanisms of resistance to ICIs. Omega-3 and polyphenol supplements are also powerful regulators of the microbiome whose influence on the immune system. Therefore, this review covers the influence of diet and probiotics on the response to immunotherapy in patients who have solid tumours.
PB Mdpi
YR 2021
FD 2021-09-01
LK http://hdl.handle.net/10668/19250
UL http://hdl.handle.net/10668/19250
LA en
DS RISalud
RD Apr 15, 2025