%0 Journal Article
%A Gordillo Hernández, Alejandra
%A Dominguez-Adame Lanuza, Eduardo
%A Cano Matias, Auxiliadora
%A Perez Huertas, Rosario
%A Gallardo Rodriguez, Katherine Maria
%A Gallinato Perez, Purificacion
%A Oliva Mompean, Fernando
%T Large gangliocytic paraganglioma of the duodenum: A rare entity.
%D 2015
%U http://hdl.handle.net/10668/2105
%X Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence.
%K Duodenum
%K Gangliocytic paraganglioma
%K Ganglion cells
%K Astenia
%K Ganglios linfáticos
%K Recurrencia local de neoplasia
%K Paraganglioma
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