RT Journal Article
T1 Case Report: Fatigue and Bleeding in a Polymedicated Patient Using Several Herbal Supplementations, Detected with g-Nomic® Software.
A1 Saldarreaga Marin, Abel
A1 Cendros, Marc
A1 Ciudad, Carlos J
A1 Sabater, Ana
K1 SNP
K1 bleeding
K1 drug-drug interaction
K1 drug-herb
K1 drug-lifestyle interactions
K1 fatigue
K1 medication risk
K1 personalized prescription
K1 pharmacogenetics
K1 pharmacogenetics software
K1 polymedication
K1 software
AB This was a case report of severe fatigue and bleeding in a 65-year-old man with ischemic heart disease who was wearing a stent and taking multiple medications for hypertension and diabetes. The use of a drug interaction and personalized prescription software (g-Nomic®) revealed potential interactions, involving acetylsalicylic acid and several non-pharmaceutical products including ginger, blueberry extracts, pineapple juice, docosahexaenoic acid and liquorice. Correction of these interactions resulted in complete remission of the reported side effects. This supports the idea that non-pharmaceuticals potentiated the effects of acetylsalicylic acid on haemostasis, producing the bleeding that would have caused fatigue. It is important to use appropriate tools to detect drug interactions that also take into account commonly used non-pharmaceutical products. Drug interactions can be considered illnesses by themselves.
SN 1178-7066
YR 2021
FD 2021-08-12
LK http://hdl.handle.net/10668/18390
UL http://hdl.handle.net/10668/18390
LA en
DS RISalud
RD Apr 7, 2025