TY  - JOUR
AU  - Nieto-González, Jose L
AU  - Gómez-Sánchez, Leonardo
AU  - Mavillard, Fabiola
AU  - Linares-Clemente, Pedro
AU  - Rivero, María C
AU  - Valenzuela-Villatoro, Marina
AU  - Muñoz-Bravo, José L
AU  - Pardal, Ricardo
AU  - Fernández-Chacón, Rafael
PY  - 2019
DO  - 10.1073/pnas.1817183116
UR  - http://hdl.handle.net/10668/13772
T2  - Proceedings of the National Academy of Sciences of the United States of America
AB  - Neural stem cells continuously generate newborn neurons that integrate into and modify neural circuitry in the adult hippocampus. The molecular mechanisms that regulate or perturb neural stem cell proliferation and differentiation, however, remain...
LA  - en
KW  - DNAJC5
KW  - adult neurogenesis
KW  - adult-onset neuronal ceroid lipofuscinosis
KW  - lysosome
KW  - synaptic neurodegeneration
KW  - Animals
KW  - Cells, Cultured
KW  - HSP40 Heat-Shock Proteins
KW  - Hippocampus
KW  - Lysosomes
KW  - Membrane Proteins
KW  - Mice
KW  - Mice, Knockout
KW  - Neural Stem Cells
KW  - Neurogenesis
KW  - Neuronal Ceroid-Lipofuscinoses
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
TI  - Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α.
TY  - research article
VL  - 116
ER  -