TY - JOUR AU - Marek-Bukowiec, K AU - Aguado, E AU - Miazek, A PY - 2016 DO - 10.1038/gene.2016.25 UR - http://hdl.handle.net/10668/10159 T2 - Genes and immunity AB - Linker for activation of T cells (LAT) is a raft-associated, transmembrane adapter protein critical for T-cell development and function. LAT expression is transiently upregulated upon T-cell receptor (TCR) engagement, but molecular mechanisms... LA - en KW - Adaptor Proteins, Signal Transducing KW - Cell Culture Techniques KW - Humans KW - Introns KW - Ionomycin KW - Jurkat Cells KW - Membrane Proteins KW - Phorbol Esters KW - Plicamycin KW - Point Mutation KW - Promoter Regions, Genetic KW - Sp1 Transcription Factor KW - Transcriptional Activation KW - Valproic Acid TI - Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription. TY - research article VL - 17 ER -