TY  - JOUR
AU  - Sanchez-Varo, Raquel
AU  - Sanchez-Mejias, Elisabeth
AU  - Fernandez-Valenzuela, Juan Jose
AU  - De Castro, Vanessa
AU  - Mejias-Ortega, Marina
AU  - Gomez-Arboledas, Angela
AU  - Jimenez, Sebastian
AU  - Sanchez-Mico, Maria Virtudes
AU  - Trujillo-Estrada, Laura
AU  - Moreno-Gonzalez, Ines
AU  - Baglietto-Vargas, David
AU  - Vizuete, Marisa
AU  - Davila, Jose Carlos
AU  - Vitorica, Javier
AU  - Gutierrez, Antonia
PY  - 2021
DO  - 10.3389/fnins.2021.752594
UR  - https://hdl.handle.net/10668/25422
T2  - Frontiers in neuroscience
AB  - Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by initial memory impairments that progress to dementia. In this sense, synaptic dysfunction and loss have been established as the pathological features that best...
LA  - en
PB  - Frontiers media sa
KW  - Alzheimer's disease
KW  - synaptic pathology
KW  - hippocampus
KW  - transgenic mice (Tg)
KW  - amyloid
KW  - oligomers
KW  - Alzheimers-disease
KW  - A-beta
KW  - Synapse loss
KW  - Dystrophic neurites
KW  - Mouse model
KW  - Precursor protein
KW  - Transgenic mice
KW  - Cognitive impairment
KW  - Memory performance
KW  - Frontal-cortex
TI  - Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis
TY  - research article
VL  - 15
ER  -