RT Journal Article
T1 Clinical-pathological characteristics and short-term follow-up associated with proliferation, apoptosis and angiogenesis in a prospective cohort of patients with colorectal tumours.
A1 Redondo, Maximino
A1 Abitei, Cristina
A1 Téllez, Teresa
A1 Fúnez, Rafael
A1 Pereda, Teresa
A1 Rodrigo, Isabel
A1 Betancourt, Ana M
A1 García-Aranda, Marilina
A1 Rueda, Antonio
A1 Martínez García, Rafael Cayetano
A1 Morales Suarez-Varela, María Manuela
A1 Zabalza, Iñaki
A1 Sánchez Del Charco, Matilde
A1 Borrero Martín, Juan José
A1 García Del Moral, Raimundo
A1 Escobar, Antonio
A1 Quintana, JoséMaría
A1 Rivas-Ruiz, Francisco
A1 REDISSEC-CARESS/CCR group, 
K1 Cell proliferation
K1 Ki-67 marker
K1 angiogenesis
K1 apoptosis
K1 colorectal neoplasms
AB We investigate the clinical and pathological features related to variations in colorectal tumour apoptosis, proliferation and angiogenesis and the influence of the latter in short-term mortality (2 years); 551 tumour samples from a prospective cohort of patients with colorectal cancer were examined and tumour biology markers were determined as follows: percentage of apoptotic cells, by the terminal deoxynucleotidyl transferase (TdT) dUTP Nick-End Labeling technique; Ki-67 antigen, as a cell proliferation marker and density of microvessels (as a marker of angiogenesis). An increase in the percentage of cellular apoptosis is significantly related to the presence of poorly differentiated tumours, with vascular invasion (p 
YR 2019
FD 2019
LK https://hdl.handle.net/10668/26902
UL https://hdl.handle.net/10668/26902
LA en
DS RISalud
RD Apr 12, 2025