%0 Journal Article
%A Redondo, Maximino
%A Abitei, Cristina
%A Téllez, Teresa
%A Fúnez, Rafael
%A Pereda, Teresa
%A Rodrigo, Isabel
%A Betancourt, Ana M
%A García-Aranda, Marilina
%A Rueda, Antonio
%A Martínez García, Rafael Cayetano
%A Morales Suarez-Varela, María Manuela
%A Zabalza, Iñaki
%A Sánchez Del Charco, Matilde
%A Borrero Martín, Juan José
%A García Del Moral, Raimundo
%A Escobar, Antonio
%A Quintana, JoséMaría
%A Rivas-Ruiz, Francisco
%A REDISSEC-CARESS/CCR group
%T Clinical-pathological characteristics and short-term follow-up associated with proliferation, apoptosis and angiogenesis in a prospective cohort of patients with colorectal tumours.
%D 2019
%U https://hdl.handle.net/10668/26902
%X We investigate the clinical and pathological features related to variations in colorectal tumour apoptosis, proliferation and angiogenesis and the influence of the latter in short-term mortality (2 years); 551 tumour samples from a prospective cohort of patients with colorectal cancer were examined and tumour biology markers were determined as follows: percentage of apoptotic cells, by the terminal deoxynucleotidyl transferase (TdT) dUTP Nick-End Labeling technique; Ki-67 antigen, as a cell proliferation marker and density of microvessels (as a marker of angiogenesis). An increase in the percentage of cellular apoptosis is significantly related to the presence of poorly differentiated tumours, with vascular invasion (p 
%K Cell proliferation
%K Ki-67 marker
%K angiogenesis
%K apoptosis
%K colorectal neoplasms
%~