TY - JOUR AU - Sanchez-Maldonado, Jose M AU - Caliz, Rafael AU - Canet, Luz AU - Horst, Rob Ter AU - Bakker, Olivier AU - den Broeder, Alfons A AU - Martinez-Bueno, Manuel AU - Canhão, Helena AU - Rodriguez-Ramos, Ana AU - Lupiañez, Carmen B AU - Soto-Pino, Maria Jose AU - Garcia, Antonio AU - Perez-Pampin, Eva AU - Gonzalez-Utrilla, Alfonso AU - Escudero, Alejandro AU - Segura-Catena, Juana AU - Netea-Maier, Romana T AU - Ferrer, Miguel Angel AU - Collantes-Estevez, Eduardo AU - Lopez Nevot, Miguel Angel AU - Li, Yang AU - Jurado, Manuel AU - Fonseca, João E AU - Netea, Mihai G AU - Coenen, Marieke J H AU - Sainz, Juan PY - 2019 DO - 10.1038/s41598-019-51255-0 UR - http://hdl.handle.net/10668/14834 T2 - Scientific reports AB - Here, we assessed whether 41 SNPs within steroid hormone genes associated with erosive disease. The most relevant finding was the rheumatoid factor (RF)-specific effect of the CYP1B1, CYP2C9, ESR2, FcγR3A, and SHBG SNPs to modulate the risk of bone... LA - en PB - Nature Publishing Group KW - Polymorphism, single nucleotide KW - Predictive value of tests KW - Prognosis KW - Retrospective studies KW - Rheumatoid factor KW - Adult KW - Aged KW - Arthritis, rheumatoid KW - Bone diseases KW - Cytochrome P-450 CYP1B1 KW - Cytochrome P-450 CYP2C9 KW - Disease progression KW - Female KW - Gonadal steroid hormones KW - Haplotypes KW - Humans KW - Male KW - Middle aged TI - Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium. TY - research article VL - 9 ER -