RT Journal Article
T1 Diplopia Is Frequent and Associated with Motor and Non-Motor Severity in Parkinson's Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up.
A1 Santos Garcia, Diego
A1 Naya-Rios, Lucia
A1 de-Deus-Fonticoba, Teresa
A1 Cores-Bartolome, Carlos
A1 Garcia-Roca, Lucia
A1 Feal-Painceiras, Maria
A1 Martinez-Miro, Cristina
A1 Canfield, Hector
A1 Jesus, Silvia
A1 Aguilar, Miquel
A1 Pastor, Pau
A1 Cosgaya, Marina
A1 Garcia-Caldentey, Juan
A1 Caballol, Nuria
A1 Legarda, Ines
A1 Hernandez-Vara, Jorge
A1 Cabo, Iria
A1 Lopez-Manzanares, Lydia
A1 Gonzalez-Aramburu, Isabel
A1 Avila-Rivera, Maria A
A1 Gomez-Mayordomo, Victor
A1 Nogueira, Victor
A1 Puente, Victor
A1 Dotor, Julio
A1 Borrue, Carmen
A1 Solano-Vila, Berta
A1 Alvarez-Sauco, Maria
A1 Vela, Lydia
A1 Escalante, Sonia
A1 Cubo, Esther
A1 Carrillo-Padilla, Francisco
A1 Martinez-Castrillo, Juan C
A1 Sanchez-Alonso, Pilar
A1 Alonso-Losada, Maria G
A1 Lopez-Ariztegui, Nuria
A1 Gaston, Itziar
A1 Kulisevsky, Jaime
A1 Blazquez-Estrada, Marta
A1 Seijo, Manuel
A1 Ruiz-Martinez, Javier
A1 Valero, Caridad
A1 Kurtis, Monica
A1 de-Fabregues, Oriol
A1 Gonzalez-Ardura, Jessica
A1 Alonso-Redondo, Ruben
A1 Ordas, Carlos
A1 Lopez-Diaz, Luis M
A1 McAfee, Darrian
A1 Martinez-Martin, Pablo
A1 Mir, Pablo
K1 PIGD
K1 Parkinson’s disease
K1 Tremor
K1 changes
K1 motor
K1 phenotype
AB Diplopia is relatively common in Parkinson's disease (PD) but is still understudied. Our aim was to analyze the frequency of diplopia in PD patients from a multicenter Spanish cohort, to compare the frequency with a control group, and to identify factors associated with it. PD patients who were recruited from January 2016 to November 2017 (baseline visit; V0) and evaluated again at a 2-year ± 30 days follow-up (V2) from 35 centers of Spain from the COPPADIS cohort were included in this longitudinal prospective study. The patients and controls were classified as "with diplopia" or "without diplopia" according to item 15 of the Non-Motor Symptoms Scale (NMSS) at V0, V1 (1-year ± 15 days), and V2 for the patients and at V0 and V2 for the controls. The frequency of diplopia in the PD patients was 13.6% (94/691) at V0 (1.9% in controls [4/206]; p  Diplopia represents a frequent symptom in PD patients and is associated with motor and non-motor severity.
PB MDPI AG
SN 2075-4418
YR 2021
FD 2021-12-17
LK https://hdl.handle.net/10668/27953
UL https://hdl.handle.net/10668/27953
LA en
NO Santos García D, Naya Ríos L, de Deus Fonticoba T, Cores Bartolomé C, García Roca L, Feal Painceiras M, et al. Diplopia Is Frequent and Associated with Motor and Non-Motor Severity in Parkinson's Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up. Diagnostics (Basel). 2021 Dec 17;11(12):2380.
DS RISalud
RD Apr 13, 2025