RT Journal Article
T1 Clinical validation of automatic local activation time annotation during focal premature ventricular complex ablation procedures.
A1 Acosta, Juan
A1 Soto-Iglesias, David
A1 Fernández-Armenta, Juan
A1 Frutos-López, Manuel
A1 Jáuregui, Beatriz
A1 Arana-Rueda, Eduardo
A1 Fernández, Marcos
A1 Penela, Diego
A1 Alcaine, Alejandro
A1 Cano, Lucas
A1 Pedrote, Alonso
A1 Berruezo, Antonio
AB Current navigation systems incorporate algorithms for automatic identification of local activation time (LAT). However, data about their utility and accuracy in premature ventricular complex (PVC) ablation procedures are scarce. This study analyses the accuracy of an algorithmic method based on automatic annotation of the maximal negative slope of the unipolar electrogram within the window demarcated by the bipolar electrogram compared with conventional manual annotation during PVC ablation procedures. Forty patients with successful ablation of focal PVC in three centres were included. Electroanatomical activation maps obtained with the automatic system (WF-map) were compared with manual annotation maps (M-map). Correlation and concordance of LAT obtained with both methods were assessed at 3536 points. The distance between the earliest activation site (EAS) and the effective radiofrequency application point (e-RFp) were determined in M-map and WF-map. The distance between WF-EAS and M-EAS was assessed. Successful ablation sites included left ventricular outflow tract (LVOT; 55%), right ventricular outflow tract (40%), and tricuspid annulus (5%). Good correlation was observed between the two annotation approaches (r = 0.655; P  Good correlation was found between M-map and WF-map. Local activation time detection was systematically delayed in WF-map, especially in LVOT. Accurate identification of e-RFp was achieved with both annotation approaches.
YR 2018
FD 2018
LK http://hdl.handle.net/10668/11770
UL http://hdl.handle.net/10668/11770
LA en
DS RISalud
RD Apr 7, 2025