TY - JOUR AU - He, Helen AU - Suryawanshi, Hemant AU - Morozov, Pavel AU - Gay-Mimbrera, Jesús AU - Del Duca, Ester AU - Kim, Hyun Je AU - Kameyama, Naoya AU - Estrada, Yeriel AU - Der, Evan AU - Krueger, James G AU - Ruano, Juan AU - Tuschl, Thomas AU - Guttman-Yassky, Emma PY - 2020 DO - 10.1016/j.jaci.2020.01.042 UR - http://hdl.handle.net/10668/15077 T2 - The Journal of allergy and clinical immunology AB - Atopic dermatitis (AD) is a prevalent inflammatory skin disease with a complex pathogenesis involving immune cell and epidermal abnormalities. Despite whole tissue biopsy studies that have advanced the mechanistic understanding of AD, single... LA - en KW - Atopic dermatitis KW - T cells KW - cytokines KW - dendritic cells KW - fibroblasts KW - single-cell RNA sequencing KW - Case-Control Studies KW - Cytokines KW - Dendritic Cells KW - Dermatitis, Atopic KW - Fibroblasts KW - Gene Expression Profiling KW - Humans KW - Immunologic Memory KW - Inflammation KW - Sequence Analysis, RNA KW - Single-Cell Analysis KW - Skin KW - T-Lymphocytes KW - Transcriptome TI - Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. TY - research article VL - 145 ER -