TY  - JOUR
AU  - Dámaso, Estela
AU  - Castillejo, Adela
AU  - Arias, María Del Mar
AU  - Canet-Hermida, Julia
AU  - Navarro, Matilde
AU  - Del Valle, Jesús
AU  - Campos, Olga
AU  - Fernández, Anna
AU  - Marín, Fátima
AU  - Turchetti, Daniela
AU  - García-Díaz, Juan de Dios
AU  - Lázaro, Conxi
AU  - Genuardi, Maurizio
AU  - Rueda, Daniel
AU  - Alonso, Ángel
AU  - Soto, Jose Luis
AU  - Hitchins, Megan
AU  - Pineda, Marta
AU  - Capellá, Gabriel
PY  - 2018
DO  - 10.1038/s41416-018-0019-8
UR  - https://hdl.handle.net/10668/25384
T2  - British journal of cancer
AB  - Constitutional MLH1 epimutations are characterised by monoallelic methylation of the MLH1 promoter throughout normal tissues, accompanied by allele-specific silencing. The mechanism underlying primary MLH1 epimutations is currently unknown. The aim of...
LA  - en
KW  - Base Sequence
KW  - Colorectal Neoplasms
KW  - Colorectal Neoplasms, Hereditary Nonpolyposis
KW  - CpG Islands
KW  - DNA Methylation
KW  - Epigenesis, Genetic
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Haplotypes
KW  - Humans
KW  - Male
KW  - MutL Protein Homolog 1
KW  - Mutation
KW  - Promoter Regions, Genetic
KW  - Sequence Analysis, DNA
TI  - Primary constitutional MLH1 epimutations: a focal epigenetic event.
TY  - research article
VL  - 119
ER  -