TY - JOUR AU - Rueda-Martínez, Carmen AU - Lamas, Oscar AU - Mataró, María José AU - Robledo-Carmona, Juan AU - Sánchez-Espín, Gemma AU - Moreno-Santos, Inmaculada AU - Carrasco-Chinchilla, Fernando AU - Gallego, Pastora AU - Such-Martínez, Miguel AU - de Teresa, Eduardo AU - Jiménez-Navarro, Manuel AU - Fernández, Borja PY - 2016 DO - 10.1093/ejcts/ezw277 UR - http://hdl.handle.net/10668/10451 T2 - European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery AB - Bicuspid aortic valve (BAV) is the most prevalent congenital cardiac malformation, frequently associated with aortic dilatation (AD). The molecular mechanisms involved in AD and its aetiological link with BAV formation are poorly understood. Altered... LA - en KW - Aetiology KW - Aortic aneurysm KW - Bicuspid aortic valve KW - Fibrillins KW - Metalloproteases KW - Aged KW - Aorta, Thoracic KW - Aortic Valve KW - Bicuspid Aortic Valve Disease KW - Female KW - Fibrillin-2 KW - Gene Expression Regulation KW - Heart Valve Diseases KW - Humans KW - Male KW - Middle Aged KW - RNA KW - Real-Time Polymerase Chain Reaction KW - Up-Regulation TI - Fibrillin 2 is upregulated in the ascending aorta of patients with bicuspid aortic valve. TY - research article VL - 51 ER -