TY  - JOUR
AU  - Hidalgo, Manuel
AU  - Galan, Jose Jorge
AU  - Sáez, Carmen
AU  - Ferrero, Eduardo
AU  - Castilla, Carolina
AU  - Ramirez-Lorca, Reposo
AU  - Pelaez, Pablo
AU  - Ruiz, Agustin
AU  - Japón, Miguel A
AU  - Royo, Jose Luis
PY  - 2008
DO  - 10.1186/1471-2407-8-110
UR  - http://hdl.handle.net/10668/1762
T2  - BMC Cancer
AB  - BACKGROUNDOn its physiological cellular context, PTTG1 controls sister chromatid segregation during mitosis. Within its crosstalk to the cellular arrest machinery, relies a checkpoint of integrity for which gained the over name of securin. PTTG1 was...
LA  - en
PB  - BioMed Central Ltd
KW  - Técnicas de Cultivo de Célula
KW  - Regulación Neoplásica de la Expresión Génica
KW  - Proteínas de Neoplasias
KW  - Línea Celular Tumoral
KW  - Metilación de ADN
KW  - Epigénesis Genética
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Culture Techniques
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Up-Regulation
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Thyroid Neoplasms
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Glandular and Epithelial::Carcinoma
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Cell Cycle Proteins::Securin
TI  - Methylation alterations are not a major cause of PTTG1 misregulation.
TY  - research article
ER  -